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See full list on mayoclinic.org Weight-loss pills — prescription drugs, nonprescription drugs, herbal products or other dietary supplements — are all, at best, tools that may help with weight loss. But there is relatively little research about these products. The best studied of these are prescription weight-loss drugs.
Four prescription weight-loss drugs are approved by the U.S. Food and Drug Administration (FDA) for long-term use: bupropion-naltrexone (Contrave), liraglutide (Saxenda), orlistat (Xenical) and phentermine-topiramate (Qsymia). Most prescription weight-loss drugs work by decreasing appetite or increasing feelings of fullness, and some do both.
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